Everyone has heard of Type 1 and Type 2 Diabetes, BUT, have you heard of Type 3 Diabetes? Research by Suzanne de la Monte, MD and Jack R. Wands, MD., shows that this new form of Diabetes is causing Alzheimer’s Disease like pathological changes in the brain leading to cognitive impairments.
Alzheimer’s Disease is the most common form of dementia, accounting for 60-80% of cases. It is a progressive disease, in which memory, thinking and reasoning skills slowly decline becoming severe enough to interfere with daily tasks.
Alzheimer’s research over the past 30 years has largely focused on the roles of two proteins called beta amyloid and tau leading to the hallmark Alzheimer brain abnormalities.
Within the last 10-15 years, research by Suzanne de la Monte, M.D., M.P.H. and her team at Brown University revealing growing evidence that Alzheimer’s is a metabolic disease caused by insulin resistance and deficiency. Based on their studies, they concluded Alzheimer’s Disease was a brain form of Diabetes due to fundamental abnormalities seen had elements of both Type 1 and Type 2 Diabetes opening the door to earlier detection and other treatment options.
This is exciting research, although we still have many unanswered questions. The good news is the research is ongoing, stay tuned!
For more information about Dr. de la Monte’s work and type 3 Diabetes, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/
For more information on Alzheimer’s Disease, https://alz.org/